Alzheimer’s Disease (AD), is now known as type 3 diabetes or “diabetes in your brain.” This claim has science behind it, but it is a bit of an oversimplification. Type 3 diabetes occurs when blood sugar becomes elevated, the neurons in the brain become unable to respond to insulin, which is essential for basic tasks, including memory and learning. Some researchers believe insulin deficiency is central to the cognitive decline of AD, and other theories blame elevated levels of insulin.
Insulin-degrading enzyme (IDE) is a zinc based, protein that breaks down insulin and amyloid β-peptide in the brain. Low levels of IDE may contribute to the buildup of amyloid plaques in the brain with hyperinsulinemia, which can lead to Alzheimer's disease
Over time, untreated diabetes can cause damage to your blood vessels, including vessels in your brain. Many people with type 2 diabetes/insulin resistance are unaware they have this condition (which could delay diagnosis and appropriate treatment), and that it could develop into AD, vascular dementia, or some other form of dementia. According to the Alzheimer’s Association, symptoms may include:
· Memory loss that affects daily living and social interactions
· Difficulty completing familiar tasks
· Misplacing things often
· Decreased ability to make judgements based on information
· Sudden changes in personality or demeanor
It is important to note that diabetes is more than elevated blood sugar, it is a risk factor for neuropathies, kidney failure, Alzheimer's, or other forms of dementia. The good news is you can improve and even reverse type 2 diabetes with dietary and lifestyle changes